Diabetes

Diabetes

 

 

Bravenboer B, Kappele AC, Hamers FP, Van Buren T, Erkelens DW, Gispen WH. Potential use of glutathione for the prevention and treatment of diabetic neuropathy in the strep-tozotocin-induced diabetic rat. Diabetologia 35:813-817, 1992 Medline

Ceriello A, Curcio F, Dello Russo P, Pegoraro I, Stel G, Amstad P, Cerutti P. The defense against free radicals protects against endothelial cells from hyperglycemia-induced plasminogen activator inhibitor 1 over-production. Blood Coagulation and Fibrinolysis 6: 133-137, 1995 Medline

Ceriello A, Giacomello R, Stel G, Motz E, Taboga C, Tonutti L, Pirisi M, Falleti E, Bartoli E. Hyperglycemia-induced thrombin formation in diabetes. The possible role of oxidative stress. Diabetes 44: 924-928, 1995 Medline

Ceriello A, Motz E, Cavarape A. Lizzio S, Russo A, Quatraro A, Giugliano D. Hyper-glycemia counterbalances the antihypertensive effect of glutathione in diabetic patients: evidence linking hypertension and glycemia through the oxidative stress in diabetes mellitus. Journal of Diabetes Complications 11: 250-255, 1997 Medline

Ciuchi E, Odetti P, Prando R. Relationship between glutathione and sorbitol concentrations in erythrocytes from diabetic patients. Metabolism 45: 611-613, 1996 Medline

Ciuchi E, Odetti P, Prando R. The effects of acute glutathione treatment on sorbitol level in erythrocytes from diabetic patients. Diabetes Metabolism 23: 58-60, 1997 Medline

Curcio F, Ceriello A. Decreased cultured endothelial cell proliferation in high glucose medium is reversed by antioxidants: new in-sights on the pathophysiological mechanisms of diabetic vascular complications. In Vitro Cell Developmental Biology 28A: 787-790, 1992 Medline

Curcio F, Pegararo I, Dello Russo P, Falleti E, Perrella G, Geriello A. SOD and GSH inhibit the high glucose-induced oxidative damage and the PDGF increased secretion in cultured human endothelial cells. Thrombolysis and Hemastasis: 74:969-973, 1995 Medline

Di Simplicio P, De Giorgio LA, Cardaioli E, Lecis R, Miceli M, Rossi R, Anichini R, Mian M, Seghieri G, Franconi F. Glutathione, glutathione utilizing enzymes and thioltransferase in platelets of insulin-dependent diabetic patients: relation with platelet aggregation and with microangiographic complications. European J of Clinical Investigation 25: 665-669, 1995 Medline

Donnine D, Zambito AM, Perrella G, Ambesi-Impiombato FS, Curcio F. Glucose may in-duce cell death through a free radical-mediated mechanism. Biochem Biophys Res Communications 219: 412-417, 1996 Medline

Jain SK, McVie R. Effect of glycemic control, race and duration of diabetes on reduced glutathione content in erythrocytes of diabetic patients. Metabolism 43: 306-309, 1994 Medline

Kakkar R, Mantha SV, Radhi J, Prasad K, Kalra J. Antioxidant defense system in diabetic kidney: a time course study. Life Science 60: 667-679, 1997 Medline

Kashiwagi A, Asahina T, Nishio Y, Ikebuchi M, Tanaka Y, Kikkawa R, Shigeta Y. Glycation, oxidative stress and scavenger activity: glucose metabolism and radical scavenger dysfunction in endothelial cells. Diabetes 45: S84-S86, 1996 Medline

Low PA, Mickander KK, Tritscler HJ. The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes 46: S38-S42, 1997 Medline

Murakami K, Kondo T, Ohtsuka Y, Fujiwara Y, Shimanda M, Kawakami Y. Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus. Metabolism 38: 753-758, 1989 Medline

Rudich A, Kozlovsky N, Potashnik R, Bashan N. Oxidant stress reduces insulin responsiveness in 3T3-Li adipocytes. American Journal of Physiology 272: E935-E940, 1997 Medline

Sundaram RK, Bhaskar A, Vijayalingam S, Viswanathan M, Mohan R, Shanmugasun-daram KR. Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications. Clinical Science 90: 255-260, 1996 Medline

Thornalley PJ, McLellan AC, Lo TW, Benn J, Sonksen PH. Negative association between erythrocyte reduced glutathione concentration and diabetic complications. Clinical Science 91: 575-582, 1996 Medline

Vijayalingam S, Parthiban A, Shanmugasun-daram KR, Mohan V. Abnormal antioxidant status in impaired glucose tolerance and non-insulin-dependent diabetes mellitus. Diabetic Medicine 13: 715-719, 1996 Medline

Yoshida K, Hirokawa J, Tagami S, Kawakami Y, Urata Y, Kondo T. Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux. Diabetologia 38: 201-210, 1995 Medline

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